The Falcons (8-5) host San Francisco (1-12) on Sunday and will be without All-Pro receiver Julio Jones for the second game because of a sprained toe.
The receiver was a game-time decision for Week 14 but was unable to play.
Quinn said on Thursday that Jones would get the green light for Sunday's game only if he could "explode pain-free" during a Friday workout. While initially believed to be turf toe, it was later revealed to be a toe sprain.
Jones has been a consistent playmaker for the franchise ever since being selected with the sixth overall pick in the 2011 NFL Draft, and now leads the league in receiving yards (1,253) despite missing last week's game against Los Angeles. Strong safety Kemal Ishmael is headed to injured reserve with the shoulder injury he suffered on Sunday against the Los Angeles Rams. The Falcons 6-foot-2, 210-pound wide receiver missed the team's Week 14 win due to a groin injury, but has been a limited participant in practice this week and "look really good" in Friday's practice, per Quinn.
Despite missing last week's game against the Rams, Jones still leads the National Football League in receiving with 1,253 yards. Sanu is our WR48, with a projection of 50 receiving yards and 0.19 touchdowns on 4 catches.
McKissic has spent the entire season on the Falcons practice squad.
Atlanta is tied for the top spot in the NFC South with the Tampa Bay Buccaneers.