Additionally, "The Five" will move into the 9 p.m. time slot starting Monday.
Bill O'Reilly has for years been Fox's most valuable on-air talent.
Embattled Fox News host Bill O'Reilly had a brief handshake with Pope Francis on Wednesday as sexual harassment allegations dog him at home.
While O'Reilly's future at the network is likely to be determined by business calculations, sources said that his failure to establish relationships has made him more vulnerable as Murdoch and his sons debate the host's future at the network.
Bill O'Reilly, 67, had a pretty interesting day today, April 19, if you ask us.
"He is an incredibly talented broadcaster who raises the bar for interviewers everywhere", she said, thanking his many loyal viewers.
21 Century Fox, Fox News's parent company, announced earlier Wednesday that O'Reilly would not return to the network.
"After a thorough and careful review of the allegations, the company and Bill O'Reilly have agreed that Bill O'Reilly will not be returning to the Fox News Channel", the company said in a statement.
Pressure on the network to fire O'Reilly has been mounting since the New York Times published a detailed report earlier this month of $13 million in settlements paid to five former employees by O'Reilly and Fox News.
The matter reached a crisis level this week because the law firm Paul Weiss is investigating a claim that O'Reilly reneged on offering a paid contributor's job to Wendy Walsh, a frequent guest on his program, after she spurned his advances at a dinner meeting in 2013.
In this combination photo, Fox News Channel personality Bill O'Reilly appears at The Hollywood Reporter's "35 Most Powerful People in Media" celebration on April 6, 2016, in NY, left, and Pope Francis leaves after celebrating Mass in Piazza Martiri Square, in Carpi, northern Italy, on April 2, 2017.
O'Reilly's public statement on Wednesday gave no indication about what he might do next.
Marc Kasowitz, O'Reilly's lawyer, said in a statement that the television host "has been subjected to a brutal campaign of character assassination that is unprecedented in post-McCarthyist America".
For American conservatives who reject the RINO establishment, O'Reilly will not be missed.
"This is what happens when women speak our truth - we can slay dragons", Bloom said.
Now, the top ratings for O'Reilly's time slot - and Fox's other prime-time shows - could be at risk.
Ruddy said he would want to know more about the issues surrounding O'Reilly's ouster from Fox.
O'Reilly and co-author Martin Dugard are due to release another book in the "Killing" series in September, and a spokeswoman for publisher Henry Holt and Co. said that plans had not changed.