Lions starting defensive end Kerry Hyder tore his Achilles and had to be carted off the field, while outside linebacker Brandon Copeland tore a pectoral muscle in the team's 24-10 win, according to NFL Network's Ian Rapoport.
With Hyder out of the rotation, young players such as Alex Barrett, Pat O'Connor and Jeremiah Valoaga will have more opportunities during the preseason to impress head coach Jim Caldwell and the defensive coaching staff.
Hyder was rushing Colts quarterback Scott Tolzien before his left leg appeared to give way, leaving the 26-year-old laying near the goal line. The Lions' 2016 sack leader with eight, Hyder's loss is a huge blow to a defense otherwise painfully short on pass rush.
"There's nobody excited about going through what he's going through", Caldwell said.
Copeland compiled 16 tackles - 11 solo and five assists - and one forced fumble past year. The Lions did not say in a release whether the Achilles was torn. Beyond Ansah, the Lions have few experienced options at defensive end. They have $7 million in 2017 cap space, enough to bring in a body or two from what the free-agent market is at this point in training camp. Just like anything else, we've got to find a way.