Neither team's star quarterbacks (Drew Brees, Philip Rivers) played and the Saints also held out star running backs Mark Ingramand Adrian Peterson along with star defensive end Cam Jordan. The pick wasn't completely Nassib's fault as it went through Tommylee Lewis' hands before safety Dexter McCoil - a Lutcher High product - caught it and returned it for a 99-yard touchdown.
Kellen Clemens subbed for Rivers and struggled for the second straight week.
In what started as a the battle of defensive cops in the first half of the game against the Browns, the Sainsts' kicker Wil Lutz drilled 22- and 42-yard field goals.
Offensively, the Saints had a ideal start as Kamara ran for a 50-yard touchdown on the first offensive snap. Lutz kicked a 26-yard field goal with 2:11 to play.
Los Angeles (0-2) had trouble moving the ball against the Saints' defense, collecting only 158 total yards. The Chargers were disappointed in their preseason opener, getting massively defeated by the Seattle Seahawks on their own home stadium, 17-48.
Led by swarming linebackers on the first- and second-team defense, the Saints beat the Chargers on Sunday night at the StubHub Center en route to a 13-7 win that gave New Orleans its first preseason victory since 2014 - ending a 10-game losing streak. They punted four times in the opening 30 minutes.
With another day of practice on Saturday, we may be in line for a third round.
Daniel finished 7 of 12 for 80 yards.
Kamara led all rushers with 61 yards on five carries.
The Chargers deepest first-half penetration was to New Orleans' 36-yard- line 1:46 before halftime when Andre Williams was tackled for a one-yard loss on fourth-and-one.
Both Brees and Rivers went through pregame workouts and were sidelined for precautionary reasons, with Brees sitting out a second game in a row. On the Chargers' final possession the Saints sacked Jones on back-to-back plays and then ended the drive with a Adam Bighill interception.